Nicotinamide mononucleotide (NMN) is a precursor to nicotinamide adenine dinucleotide (NAD+), a molecule essential for cellular function. NAD+ acts as a coenzyme, aiding enzyme activity involved in energy metabolism, gene expression, and mitochondrial regulation.
NAD+ levels naturally decrease with age due to reduced production and increased consumption, impacting health and potentially leading to age-related diseases. NMN supplements offer a solution by promoting NAD+ synthesis, potentially benefiting overall health and aging. Know more about: NMN Supplements UK
Benefits of NMN:
- Boosting NAD+ Levels:* Limited research suggests NMN supplementation may raise NAD+ levels, especially in certain groups. A study with healthy adults found that 250 mg of NMN daily for 12 weeks significantly increased blood NAD+ levels. Another study on middle-aged adults taking 300 mg, 600 mg, or 900 mg doses daily for 60 days revealed higher blood NAD+ concentrations in the 600 mg and 900 mg groups.
- Enhancing Physical Performance and Wellbeing:* NAD+ plays a crucial role in energy production. NMN supplements could improve physical performance and energy levels. Studies showed NMN supplementation led to increased walking distances and better general health in middle-aged adults. Runners taking NMN had improved aerobic capacity, and older men experienced enhanced gait speed and grip strength after NMN supplementation.
- Improving Metabolic Health:* NMN could enhance metabolic health by improving insulin sensitivity. Studies on postmenopausal women with prediabetes demonstrated increased insulin signaling and sensitivity with NMN supplementation. Intravenous NMN treatment might also reduce triglyceride levels, though research is limited.
- Lengthening Telomeres:* NMN might contribute to telomere lengthening, which plays a role in aging. Studies on mice and human participants showed NMN supplementation led to longer telomeres.
Taking NMN:
NMN is present in the body and certain foods. Supplements come in various forms, with dosages ranging from 250 mg to over 1,250 mg. Most supplements contain around 200 mg of NMN per capsule.
Safety and Interactions:
NMN is generally considered safe, with no reported adverse effects up to 1,250 mg. However, further research is needed to understand long-term impacts.
Choosing NMN Supplements:
Select NMN supplements from companies that undergo third-party testing for purity and quality. Certifications from organizations like U.S. Pharmacopeia and NSF International are indicative of safety. Consider allergen information and interactions with other ingredients.
Conclusion:
NMN holds promise in enhancing NAD+ levels and overall health, though comprehensive research is required. While NMN supplements offer potential benefits in physical performance and metabolic health, approach them with cautious optimism given limited research. Always consult a healthcare provider before adding new supplements to your routine.